| ncRNA name | FAK siRNA |
| ncRNA Category | siRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | RPE cells, choroidal microvascular endothelial cells (CECs) |
| Methods | immunohistochemistry, Western blot, siRNA transfection, semi-qRT-PCR, ELISA |
| Expression pattern | associated |
| Functional description | The absence of FAK effectively reduced the expression of hypoxia-induced HIF-1alpha and VEGF in RPE cells, resulting in the inhibition of proliferation and migration of choroidal microvascular endothelial cells (CECs). |
| PubMed ID | 19111720 |
| Year | 2009 |
| Title | Focal adhesion kinase signaling pathway participates in the formation of choroidal neovascularization and regulates the proliferation and migration of choroidal microvascular endothelial cells by acting through HIF-1 and VEGF expression in RPE cells. |
| Drug-related ncRNA | NO |
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